DLK1 Antibody

ArtNr	ABC-ASC11539
Hersteller	Abcepta
Menge	100 ug
Kategorie	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies Obesity Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Primary
Applikationen	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Smas CM and Sul HS. Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 1993; 73:725-34. Sul HS. Mini-review: Pref-1: role in adipogenesis and mesenchymal cell fate. Mol. Endocrinol. 2009; 23:1717-25. Kawakami T, Chano T, Minami K, et al. Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma. Hum. Mol. Genet. 2006; 15:821-30. Wermter AK, Scherag A, Meyre D, et al. Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdomainance in human. Eur. J. Hum. Genet. 2008; 16:1126-34.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Applications	DLK1 antibody can be used for detection of DLK1 by Western blot at 1 - 2 µg/mL.
Manufacturer - Category	Primary Antibodies; Neuroscience; Signal Transduction; Stem Cells
Manufacturer - Targets	DLK1; At least four isoforms of DLK1 are known to exist.
Storage Conditions	DLK1 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	DLK1 Antibody: The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
Clonality	Polyclonal
Gene Name	DLK1
Reactivity	H, M, Rat
Calculated Molecular Weight	41300
Antigen Source	homo sapiens
Purification	DLK1 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	DLK1 antibody can be used for detection of DLK1 by Western blot at 1 - 2 µg/mL.
Positive Control	HepG2 Cell Lysate
Buffer	DLK1 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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