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KRT80 Antibody

ArtNr PRS-55-483-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Langbein, L., et al. J. Biol. Chem. 285(47):36909-36921(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)
NCBI KRT80
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20, KRT80, KB20
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:1000
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
51 kDa
Manufacturer - Research Area
Signal Transduction
Background
Keratins are intermediate filament proteins responsiblefor the structural integrity of epithelial cells and are subdividedinto epithelial keratins and hair keratins. This gene's expressionprofile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type IIhair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages ofdifferentiation but then dispersing throughout the cytoplasm interminally differentiating cells. The type II keratins areclustered in a region of chromosome 12q13. Two transcript variantsencoding two different fully functional isoforms have been foundfor this gene.
Protein Gi #
166218808
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Clonality
Polyclonal
NCBI Official Name
Keratin, type II cytoskeletal 80
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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