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Anti-CD86 Antibody [SPM600] - BSA and Azide free Europäischer Partner

ArtNr ANTI-A253826-100
Hersteller Antibodies.com
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen IF, IHC-P
Clon SPM600
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Storage Conditions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Product Description
Mouse monoclonal [SPM600] antibody to CD86.
Clonality
Monoclonal
Immunogen
Recombinant full-length human CD86 protein.
Concentration
1 mg/ml
Manufacturer - Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Purification
Protein A/G chromatography.
Recommended dilutions
IF: 1-2 µg/ml, IHC-P: 2-4 µg/ml
Molecular weight
70 kDa
Manufacturer - Specificity
This antibody recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkins disease.
Light chain
kappa

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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