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SOX3 (SRY (sex determining region Y)-box 3)

ArtNr 18-003-43229
Hersteller GENWAY
Menge 0.1 mg
Kategorie
Typ Antibody
Applikationen WB
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-D5AEFB
Similar products 18-003-43229
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Genway ID:
GWB-D5AEFB
Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human SOX3.
ELISA Titre:
1:1562500
Note:
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a pro
Subcellular Location:
Nucleus.
Disease:
Defects in SOX3 are the cause of infundibular hypoplasia and hypopituitarism [MIM:313430].
Disease:
Defects in SOX3 are the cause of mental retardation X-linked with isolated growth hormone deficiency (MRXGH) [MIM:300123].
Similarity:
Contains 1 HMG box DNA-binding domain. Summary: This protein is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. Savare. J. . et al. . (2005) Mol. Biol. Cell 16 (6). 2660-2669.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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