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PIGP Polyclonal Antibody

ArtNr ABK-ABP59912-30ul
Hersteller Abbkine Scientific
Menge 30 ul
Quantity options 100 ul 200 ul 30 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Phosphatidylinositol N-acetylglucosaminyltransferase subunit P,Down syndrome critical region protein 5,Down syndrome critical region protein C,Phosphatidylinositol-glycan biosynthesis class P protein,PIG-P
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Manufacturer - Applications
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Shipping Temperature
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background
PIGP (Phosphatidylinositol Glycan Anchor Biosynthesis Class P) is a Protein Coding gene. Diseases associated with PIGP include Epileptic Encephalopathy, Early Infantile, 55 and Epileptic Encephalopathy, Early Infantile, 15. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Metabolism. PIGP encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). PIGP is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. PIGP has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described.
Formulation
Liquid solution
Immunogen
Synthesized peptide derived from part region of human PIGP protein at amino acid sequence of 70-150
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Concentration
1 mg/ml
Other information
The antibody detects endogenous levels of PIGP protein
Storage Buffer
PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 30 ul
Lieferbar: In stock
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