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Mouse Anti-Human CASP8 Active Clone C502S Affinity Purified mAb

Mouse Anti-Human CASP8 Active Clone C502S Affinity Purified mAb

ArtNr	CS-CMC435
Hersteller	Cell Sciences
Menge	100 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	C502S
Specific against	Human
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	MCH5, CAP4, FLICE, MACH, apoptosis-related cysteine protease, ALPS2B, FLJ17672, MGC78473, FADD-homologous ICE/CED-3-like protease, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein, OTTHUMP00000163720, caspase 8, caspase 8, cysteine protease, Mch5 isoform alpha, OTTHUMP00000163718, OTTHUMP00000163719, procaspase-8
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Description	Mouse Anti-Human Active Caspase 8 Clone C502S Affinity Purified monoclonal antibody. Caspase 8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase 8 is synthesized as inactive pro-enzyme. Activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase 8 is able to cleave and activate downstream caspases, such as caspase 3, -6, -7 and a death agonist member of the BCL2/BCL-xL family, Bid, leading to apoptosis.
Formulation	Liquid in PBS + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles .
Specificity	Detects the 10 kDa small subunit of human Caspase 8. Does not detect the full length Caspase 8.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

CS-CMC435.pdf

CS-CMC435-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 11.10.2024

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