Mouse Anti-Human CASP8 Active Clone C502S Affinity Purified mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon C502S
Isotype IgG1
Applikationen WB
Menge 100 ug
Host Mouse
ArtNr CS-CMC435
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunoprecipitation
Description
Mouse Anti-Human Active Caspase 8 Clone C502S Affinity Purified monoclonal antibody. Caspase 8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase 8 is synthesized as inactive pro-enzyme. Activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase 8 is able to cleave and activate downstream caspases, such as caspase 3, -6, -7 and a death agonist member of the BCL2/BCL-xL family, Bid, leading to apoptosis.
Formulation
Liquid in PBS + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the 10 kDa small subunit of human Caspase 8. Does not detect the full length Caspase 8.
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles .
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 863,97 €
Preis: 863,97 €
lieferbar

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Arbeitsanleitung

CS-CMC435.pdf