Mouse Anti-Human IL-6 clone UC-6 mAb

IL-6 is a cytokine that functions in inflammation and the maturation of B cells. In addition, it has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The malfunction of IL-6 has been associated with a wide range of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Dissolve the contents of the vial by injection of 0.5 ml sterile distilled water.

Binds with similar affinity to natural and recombinant human IL-6. Shows full cross-reactivity with IL-6 from several Old World monkeys