Mouse Anti-Human IL-6 clone UC-6 mAb

IL-6 is a cytokine that functions in inflammation and the maturation of B cells. In addition, it has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The malfunction of IL-6 has been associated with a wide range of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Ion exchange chromatography.

Lyophilized product is stable for at least one year at 2-4C. After reconstitution, the contents can be safely stored at 2-4C for one month or for one year at -20C to -80C. In solution, add 0.02% sodium azide to prevent bacterial growth.