Antibodies

Mouse Anti-Human LBP Clone biG 42 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon biG42
Isotype IgG1
Applikationen WB, ELISA
Menge 100 ug
Host Mouse
ArtNr CS-CML002
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot, ELISA, Immunohistology. LBP inhibition studies: no inhibition of LPS binding to membrane bound CD14. Binding titre at human LBP-ELISA is 1:10, 000. The binding site is not directly involved in LBP-LPS-CD14 interaction. The optimal concentration should be determined by the user for each specific application.
Description
Mouse Anti-human LBP Clone biG 42 monoclonal antibody. LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Formulation
Lyophilized in PBS without preservatives or additives
Specificity
Human LBP
Immunogen
Immunoaffinity purified recombinant human LBP
Purification
Protein G purification
Reconstitution
Centrifuge vial prior to opening. Add 100 ul sterile distilled water to the vial to fully solubilize the antibody.
Storage and Stability
Store at -20C to -80C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/ml

Arbeitsanleitung

CS-CML002.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 537,87 €
Preis: 537,87 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de