Mouse Anti-Human LBP Clone biG 412 mAb

Hersteller Cell Sciences
Kategorie Produkte / Antibody
Typ Antibody
Specific against Human
Clon biG412
Isotype IgG1
Applikationen ELISA
Menge 100 ug
Host Mouse
ArtNr CS-CML004
Eclass 6.1 32160702
Eclass 9.0 32160702
ELISA: Binding titer for human LBP ELISA: 1:5, 000. LBP inhibition studies: Inhibits LPS binding to membrane bound CD14, Inhibition titer: 1:1000. Antibody directly influences the interaction of CD14-LPS-LBP. The binding site is at the C-terminal site of LBP. The optimal concentration should be determined by the user for each specific application.
Mouse monoclonal antibody against human LBP Clone biG 412 LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Lyophilized in PBS with no preservatives or additives
Recombinant human LBP
Protein G purified
Centrifuge vial prior to opening. Reconstitute with 50 ul sterile distilled water
Storage and Stability
Store at -20C to -80C. Avoid repeated freeze-thaw cycles.
2 mg/ml
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 488,97 €
Preis: 488,97 €

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