Mouse Anti-Human PDGFBB mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG2
Applikationen WB
Menge 100 ug
Host Mouse
ArtNr CS-CMP107
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot The optimal concentration should be determined by the user for each specific application.
Description
Platelet-Derived Growth Factor beta (PDFGB) is a member of the Platelet-Derived Growth Factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer (PDGF-AB) with Platelet-Derived Growth Factor alpha (PDGFA), where the dimers are connected by disulfide bonds. Mutations in the, PDGFB, gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for, COL1A1, are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Formulation
Lyophilized from sterile filtered solution in PBS
Specificity
Recognizes Human PDGF-BB
Immunogen
Recombinant Human PDGF-BB
Purification
Protein G affinity chromatography
Reconstitution
Centrifuge vial prior to opening. Reconstitute with sterile distilled water.
Storage and Stability
Stable below -20C. After reconstitution, stored in working aliquots below -20C for at least six months. Avoid repeated freeze-thaw cycles.
GeneID
5155
Cross-Reactivity
40% cross-reactivity with rPDGF-AB and no cross-reactivity with rPDGF-AA
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 659,93 €
Preis: 659,93 €
lieferbar

Angebot anfordern

Fragen zum Produkt?

Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de

Arbeitsanleitung

CS-CMP107.pdf