Mouse Anti-Human E-Selectin/CD62E Clone 9E7 mAb

Mouse Anti-Human E-Selectin/CD62E monoclonal antibody clone 9E7 E-Selectin is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat domains that contain 6 conserved cysteine residues. E-Selectin is a part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Recognizes Human E-Selectin/CD62E

Protein G affinity chromatography

Lyophilized antibody is stable for 2 years from date of receipt when stored at -80C. Reconstituted antibody can be aliquoted and stored frozen at -20C to -80C for at least six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

For Western Blot, use a working dilution of 1:500-2000.For Immunohistochemistry (Paraffin sections), use a working dilution of 1:50-200.The optimal concentration should be determined by the user for each specific application.