Rabbit Anti-Human BAX Affinity Purified pAb

ArtNr	CS-CPB116
Hersteller	Cell Sciences
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Cell Biology Cell Status Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL2L4, apoptosis regulator BAX
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Storage Conditions	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Application Notes	For Western Blot, use a working dilution of 0.5-4 ug/ml.For Immunoprecipitation, use a working dilution of 10-20 ug/ml.Blocking Peptide (Cat. No. CPB116BP) is available separately.The optimal concentration should be determined by the user for each specific application.
Cross-Reactivity	Reacts with human, mouse, rat, and monkey.
Description	Rabbit Anti-Human BAX Affinity Purified polyclonal antibody. The BCL2 family proteins function to either inhibit (BCL2 and BCL-xL) or promote (BAX and BAK) apoptosis. BAX contains the conserved BCL2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with BCL2. When BCL2 is in excess, apoptosis is inhibited. However, if BAX levels increase in response to a death signal, the cell is pushed toward death.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide corresponding to the amino acids near the N-terminus of human BAX
Purification	Biospecific affinity chromatography
Specificity	Detects a 20 kDa protein, corresponding to the apparent molecular weight of BAX on SDS-PAGE immunoblots.
Concentration	0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CS-CPB116-datasheet.pdf

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Menge: 100 ug

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