Antibodies

Rabbit Anti-Human CASP3 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPC115
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Human Caspase 3 Affinity Purified polyclonal antibody. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase 3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase 3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g. PARP and DFF).
Formulation
Liquid in PBS, pH 7.2 + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects proform and the cleaved large fragment of caspase 3.
Immunogen
Synthetic peptide corresponding to the C-terminus of human caspase 3 large fragment
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, and rat.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 687,50 €
Preis: 687,50 €
lieferbar

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Arne Pelz

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Arbeitsanleitung

CS-CPC115.pdf