Antibodies

Rabbit Anti-Human CASP8 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPC117
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunohistochemistry
Description
Rabbit Anti-Human Caspase 8 Affinity Purified polyclonal antibody. The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase 8 involves a two-step proteolysis: the cleavage of caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the 26 kDa fully cleaved fragment and the 35-43 kDa intermediate of human Caspase 8 in apoptotic samples.
Immunogen
Synthetic peptide surrounding the cleavage site of human Caspase 8
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for longer storage. Avoid repeated freeze-thaw cycles.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 599,26 €
Preis: 599,26 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

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Arbeitsanleitung

CS-CPC117.pdf