Antibodies

Rabbit Anti-Human CASP10 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 200 ug
Host Rabbit
ArtNr CS-CPC128
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Human Caspase 10 Affinity Purified polyclonal antibody. Caspase family of cysteine proteases play a key role in apoptosis. Caspase 10 is expressed in many tissues and cell lines, and has been identified as caspase 10/a (short form) and caspase 10/b (long form), respectively. Similar to other caspases, caspase 10 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Activated caspase 10 activates caspase 3, -4, -6, -7, -8, and –9, which are then involved in proteolytic cleavage of many cellular proteins. Caspase 10 has been shown to be involved in the Fas and TNFR1 induced apoptosis.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the proform (ca. 55 kDa), intermediates (30 kDa and 34 kDa), and cleaved form, (ca. 20 kDa) of Caspase 10.
Immunogen
Synthetic peptide surrounding amino acid 404 of human Caspase 10
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, and rat.
Menge: 200 ug
Lieferbar: In stock
Listenpreis: 841,18 €
Preis: 841,18 €
lieferbar

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