Vergleich

Rabbit Anti-Human VEGFR1/FLT1 pAb

ArtNr CS-CPV004A
Hersteller Cell Sciences
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products VEGFR1, vascular permeability factor receptor, VEGFR-1, FLT, vascular endothelial growth factor receptor 1, FLT-1, fms-like tyrosine kinase 1, tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT
Lieferbar
Manufacturer - Category
Antibodies
Storage Conditions
Lyophilized antibody is stable at room temperature for up to one month but is best stored at -20C. After reconstitution, stable for two weeks in working aliquots at 2-8C. Frozen aliquots are stable for at least six months when stored at -20C. Avoid repeated freeze-thaw cycles.
Description
Rabbit Anti-human VEGFR1/FLT1 polyclonal antibody. Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 (sVEGFR-1) was found in HUVE supernatants in 1996, which is generated by alternative splicing of the flt-1 mRNA.
Formulation
Lyophilized from PBS.
Immunogen
Recombinant human soluble Flt1 (D1-5).
Purification
Protein A chromatography
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1-1.0 mg/mL.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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