Rabbit Anti-Human FGFR1 pAb

ArtNr	CS-CSI10175
Hersteller	Cell Sciences
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Cell Biology Cell Culture Cytokines Western Blot Primary Antibodies Astrocytoma By Organ Bladder Cancer Colorectal Cancer Calcium Binding Protein Markers Interneuron Markers
Typ	Antibody Polyclonal
Applikationen	WB
Clon	Poly6162
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, hydroxyaryl-protein kinase, CD331, FLJ99988, KAL2, N-SAM, OGD, FMS-like tyrosine kinase 2, OTTHUMP00000190881, basic fibroblast growth factor receptor 1, fms-related tyrosine kinase 2, OTTHUMP00000190874, OTTHUMP00000190878, OTTHUMP00000190879, fms-related tyrosine kinase-2, heparin-binding growth factor receptor, soluble FGFR1 variant 1, soluble FGFR1 variant 2
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Storage Conditions	Upon receipt, store frozen at -20C. Avoid repeated freeze-thaw cycles.
Description	FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. This receptor can be upregulated by TGF-beta1 in lung fibroblasts and by platelet derived growth factor-BB in fibroblasts. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM. ThePoly6162 antibody recognizes human FGFR1 (multiple isoforms) and has been shown to be useful for Western blot.
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Recombinant (partial), N-terminal
Purification	The antibody was purified by antigen-affinity chromatography.

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