Rabbit Anti-Human KIF11 Phospho-Thr927 Clone Poly6205 pAb

hEg5 (also known as kinesin-like protein KIF11, kinesin-related motor protein Eg5, kinesin-like spindle protein HKSP, and thyroid receptor interacting protein 5 (TRIP5)) is a 119 kD kinesin-like protein family, BimC subfamily. This protein is a catalytic kinesin motor with coiled-coil and Smc domains. hEg5 is localized at the centrosomes, spindle microtubules, and intracellular bridge. This motor protein is required for establishing the bipolar spindle. hEg5 is modified by phosphorylation on Thr927 by Cdc2 to allow association with the spindle apparatus. hEg5 has been shown to interact with the thyroid hormone receptor in presence of thyroid hormone and Cdc2. The Poly6205 antibody has been shown to react with phosphorylated human Eg5 (Thr927) by Western blot.

Modified peptide

0.5 mg/ml