Mouse Anti-Monkey IL-13 clone QS-13 mAb

Antibodies

Mouse Monoclonal Antibody against Monkey IL-13 Clone QS-13 was produced, in vitro, using serum free medium. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. It is involved in several stages of B-cell maturation and differentiation. IL-13 up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. It down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines. IL-13 is critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

Ion exchange chromatography.

Binds with high efficiency to natural rhesus macaque, cynomolgus monkey, pigtailed macaque, Japanese macaque, barbary macaque, lion-tailed macaque, baboon, African green monkey and marmoset IL-13.