Rat Anti-Mouse VEGFA mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Clon 2G02
Isotype IgG2
Applikationen WB
Menge 100 ug
Host Rat
ArtNr CS-CMV105
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot: (1:400-800) Immunohistochemistry: (1:50-100) The optimal concentration should be determined by the user for each specific application.
Description
Rat Anti-Mouse VEGFA monoclonal antibody. Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Formulation
Lyophilized from a 0.2 um sterile filtered solution in PBS
Specificity
Recognizes mouse VEGF164 and VEGF120
Immunogen
Recombinant mouse VEGF (isoform 164), a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
Purification
Protein G affinity chromatography
Reconstitution
Centrifuge vial prior to opening. Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.
Storage and Stability
Store lyophilized antibody at -80C. Reconstituted antibody is stable for at least six months in working aliquots at -80C. Avoid repeated freeze-thaw cycles.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 731,98 €
Preis: 731,98 €
lieferbar

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