|
Hersteller |
Cell Sciences |
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Mouse |
|
Clon |
2G02 |
|
Isotype |
IgG2 |
|
Applikationen |
WB |
|
Menge |
100 ug |
|
Host |
Rat |
|
ArtNr |
CS-CMV105 |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
Western Blot: (1:400-800) Immunohistochemistry: (1:50-100) The optimal concentration should be determined by the user for each specific application. |
| Description |
Rat Anti-Mouse VEGFA monoclonal antibody. Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product. |
| Formulation |
Lyophilized from a 0.2 um sterile filtered solution in PBS |
| Specificity |
Recognizes mouse VEGF164 and VEGF120 |
| Immunogen |
Recombinant mouse VEGF (isoform 164), a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains. |
| Purification |
Protein G affinity chromatography |
| Reconstitution |
Centrifuge vial prior to opening. Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml. |
| Storage and Stability |
Store lyophilized antibody at -80C. Reconstituted antibody is stable for at least six months in working aliquots at -80C. Avoid repeated freeze-thaw cycles. |
