|
Hersteller |
Cell Sciences |
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Mouse |
|
Isotype |
IgG |
|
Applikationen |
WB |
|
Menge |
100 ug |
|
Host |
Rabbit |
|
ArtNr |
CS-CPC111 |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
Western Blot |
| Description |
Rabbit Anti-Mouse Caspase 2 Affinity Purified polyclonal antibody. Caspases play a key role in apoptosis. Similar to other caspases, caspase 2 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase 2 mRNA is alternatively spliced. The larger mRNA species encoding a product of 435 amino acids is known as ICH-1L. The smaller mRNA species encoding a protein of 312 amino acids is named ICH-1S. Over expression of ICH-1L induces apoptosis, while over expression of ICH-1S suppresses Rat-1 cell death induced by serum deprivation. |
| Formulation |
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only. |
| Specificity |
Detects the full length and small subunit of caspase 2. In human samples, it also detects a 30 kDa intermediate fragment. |
| Immunogen |
Synthetic peptide surrounding amino acid 417 of mouse caspase 2 |
| Purification |
Biospecific affinity chromatography |
| Storage and Stability |
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles. |
| Cross-Reactivity |
Reacts with human, mouse, and rat. |
