Antibodies

Rabbit Anti-Mouse Casp2 Affinity Purified pAb

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Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPC111
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Rabbit Anti-Mouse Caspase 2 Affinity Purified polyclonal antibody. Caspases play a key role in apoptosis. Similar to other caspases, caspase 2 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase 2 mRNA is alternatively spliced. The larger mRNA species encoding a product of 435 amino acids is known as ICH-1L. The smaller mRNA species encoding a protein of 312 amino acids is named ICH-1S. Over expression of ICH-1L induces apoptosis, while over expression of ICH-1S suppresses Rat-1 cell death induced by serum deprivation.
Formulation
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the full length and small subunit of caspase 2. In human samples, it also detects a 30 kDa intermediate fragment.
Immunogen
Synthetic peptide surrounding amino acid 417 of mouse caspase 2
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, and rat.

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Menge: 100 ug
Lieferbar: In stock
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