Rabbit Anti-Mouse CXCL12/SDF-1 alpha pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Isotype IgG
Applikationen WB
Menge 200 ug
Host Rabbit
ArtNr CS-CPS000
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western blot: working dilution of 1:1, 000 Immunohistochemistry: working dilution of 1:100-1:500 The optimal concentration should be determined by the user for each specific application.
Description
Chemokine (C-X-C motif) Ligand 12 (CXCL12), also known as Stromal Cell-Derived Factor 1 alpha (SDF-1 alpha), is a 70-amino acid chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of CXCL12 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. CXCL12/SDF-1 has been shown to be chemotactic for lymphocytes. In addition, CXCL12/SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T-cells. CXCL12/SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Formulation
Lyophilized with 0.1% sodium azide. Precaution: This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Mouse SDF-1 alpha
Immunogen
Recombinant Mouse SDF-1 alpha, a 70-amino acid CXC chemokine.
Purification
Protein A purified
Reconstitution
Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 ul sterile water.
Storage and Stability
Store at 4C for short term storage. For long term storage, aliquot and store at -20C. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with both mouse and rat SDF-1 alpha. Cross-reactivity to SDF-1 alpha of additional species has not been determined.
Menge: 200 ug
Lieferbar: In stock
Listenpreis: 404,42 €
Preis: 404,42 €
lieferbar

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