Rabbit Anti-Porcine TGF-beta pAb

Catalog Number: CPT001Lot Number: 100414Content: Protein A purified rabbit IgG, 500 ig, with 0.1% sodium azide, lyophilized.(Reconstitute to 1 mg/ml by adding 500 il H20)Product Description and Usage: For research use only. This polyclonal antibody, which also reacts with mouse, rat and human TGFa1, was generated using E. coli-expressed porcine TGFa1 as an immunogen. The tested titer for Western blot is 1:2, 000, and 1:200-1:500 for immunohistochemistry.Cross-reactivity to TGFa1 of other species has not been determined.Storage Condition: 4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze and thaw.Background: TGFa1 (transforming growth factor-beta1) is a family of multifunctional 25 kDa proteins. TGFa1 was originally identified for its ability to induce the growth of normal rodent fibroblasts in soft agar. It is now known that TGFa1 is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth, development and tissue remodeling following injury. TGFa1 is produced as latent high molecular weight complexes. The activation of latent TGFa1 is an important step in the regulation of its action.