|
Hersteller |
Cell Sciences |
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Rat |
|
Isotype |
IgG |
|
Applikationen |
WB |
|
Menge |
0.5 mg |
|
Host |
Rabbit |
|
ArtNr |
CS-CPF203 |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
Western blot: working dilution of 1:1, 000-1:2, 000 Immunohistochemistry: working dilution of 1:100-1:500 The optimal concentration should be determined by the user for each specific application. |
| Description |
Rabbit Anti-Rat Fractalkine/CX3CL1 Neutralizing polyclonal antibody. CX3CL1 is a membrane-bound CX3C chemokine. The mature protein is part of a 397-amino acid precursor consisting of a chemokine domain (76 amino acids), a mucin stalk of 241 residues, a putative transmembrane domain (18 amino acids), and an intracellular tail of 37 amino acids. Within the chemokine domain, the first two cysteine residues are separated by 3 amino acids. Fractalkine message is found at high concentrations in the brain, and also in kidney, lung and heart. CX3CL1 is chemotactic for monocytes and may play a role in brain inflammation. |
| Formulation |
Lyophilized with 0.05% sodium azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only. |
| Specificity |
Recombinant and natural rat fractalkine |
| Immunogen |
Recombinant chemotactic domain of rat CX3CL1 |
| Purification |
Protein A purified |
| Reconstitution |
Centrifuge vial prior to opening. Add 500 ul sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml. |
| Storage and Stability |
Store at 4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze-thaw cycles. |
| Cross-Reactivity |
Less than 20% cross-reactivity to human CX3CL1. Cross-reactivity to CX3CL1 of other species has not been determined. |
