Description |
IP-10 (interferon-gamma induced protein 10 kD, in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3. |
Formulation |
Protein A purified rabbit IgG, 0.2mg, with 0.1% sodium azide, lyophilized. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only. |