Rabbit Anti-Rat MCP-1 pAb

Rat MCP-1 is a 148 amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. It was originally cloned from a Con A-stimulated rat spleen cDNA library. This rat MCP-1 is 49 amino acids longer than human MCP-1 at the 3' end. This 3' end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and which explains the higher molecular weight (25 kDa). in vitro , MCP-1 is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophils. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli.

Recombinant Rat MCP-1

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 500 ul sterile water.

Rat MCP-1