Rabbit Anti-Rat VEGFC pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Rat
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPV005A
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western blot. The optimal concentration should be determined by the user for each specific application.
Description
Rabbit anti-rat VEGFC polyclonal antibody. VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
Formulation
Lyophilized from PBS, pH 7.4
Specificity
Rat VEGFC
Immunogen
Highly purified recombinant rat dNdC VEGFC
Purification
Protein A chromatography
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water to the vial to fully solubilize the antibody to a concentration of 0.1-1.0 mg/ml.
Storage and Stability
Lyophilized antibody is stable for 1 month at 2-4C and for 1 year at -20C to -80C. Reconstituted antibody is stable for six weeks at 2-4C. Avoid repeated freeze-thaw cycles.

Arbeitsanleitung

CS-CPV005A.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 398,34 €
Preis: 398,34 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de