Recombinant Human IGF1 (Leu24/Ala31) Receptor Grade

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
Host E.coli
ArtNr CS-ADU020
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Human [Leu24] [Ala31] Insulin-like Growth Factor-I (IGF-I) is an analog of human IGF-I with a Leu substitution in place of Tyr at position 24 and an Ala for Tyr at position 31 of the human IGF-I sequence. Human [Leu24] [Ala31], IGF-I has greatly reduced binding to the Type 1 IGF receptor and to the insulin receptor compared to IGF-I, [Leu24] IGF-I and [Leu60] IGF-I. Human[Leu24] [Ala31] IGF-I has normal binding to acid-stripped human serum binding proteins. Consequently human [Leu24] [Ala31] IGF-I is an extremely useful analog of IGF-I for investigating IGF actions largely independent of binding to the Type 1 IGF receptor.
Source
E. coli
Molecular Weight
7.507 kDa
Purity
Greater than 95% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per ug (1EU/ug).
Biological Activity
Type 1 IGF receptor binding assay ñ ED50 >750 ng/ml IGF binding protein assay ñ ED50, 2000 ng/ml
Format
Lyophilized
Menge: 20 ug
Lieferbar: In stock
Listenpreis: 368,02 €
Preis: 368,02 €
lieferbar

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