Recombinant Human IGFBP5

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
ArtNr CS-BP5BU020
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Human Insulin-like Growth Factor Binding Protein-5 (IGFBP-5) is a 252 amino acid protein that is one of the six iclassicali IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. Like hIGFBP-3 it forms a ternary complex with an acid-labile subunit (ALS). hIGFBP-5 preferentially binds IGF-II and it also binds with high affinity to extracellular matrix components which protect it from proteolysis. IGFBP-5 has a nuclear targeting sequence and, independent of the presence of IGF-I, fluorescently labeled IGFBP-5 is translocated to the nucleus of actively dividing cells. The significance of this observation is not yet understood.
Source
Produced recombinantly in mammalian cells. Purified by affinity and other chromatographic steps.
Molecular Weight
31 - 32 kDa
Purity
Greater than 95% by HPLC and N-terminal sequencing
Biological Activity
Detected by immunoblot using an antibody specific for human IGFBP-5.
Format
Lyophilized
Menge: 20 ug
Lieferbar: In stock
Listenpreis: 543,94 €
Preis: 543,94 €
lieferbar

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