| Description |
Acyl CoA dehydrogenase is the enzymeused to catalyzethe first step of ?-oxidationin Fatty acid metabolism. Acyl-coenzyme A (CoA) dehydrogenases (ACADs) are a family of mitochondrial enzymes that catalyze the first dehydrogenation step in the bets-oxidation of fatty acyl-CoA derivatives. Several human ACADs exist and all ACADs catalyze the same initial dehydrogenation of the substrate at the beta-carbon atom and require electron transfer flavoprotein as an alectron acceptor. The predicted 415-amino acid ACAD8 protein contains many of the residues conserved in most other ACADs, including an active site glutamic acid residue and residues important for tetramer formation. Acyl-Coenzyme A Dehydrogenase 8 Human Recombinant produced in, E. coli, is a non-glycosylated, polypeptide chain containing amino acids 1-415 and having a total MW = 47.7 kda. ACAD8 contains T7 tag at the N-terminus. ACAD-8 is purified by proprietary chromatographic techniques. |
| Formulation |
Sterile Filtered clear solution. Recombinant human Acyl-Coenzyme A Dehydrogenase 8 at a concentration of 0.1 mg/ml in 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3, 10 mM DTT. |
