Recombinant Human Apolipoprotein E3

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 500 ug
Host E.coli
ArtNr CS-CRA401B
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Apolipoprotein E (Apo-E) belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Apo-E exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human APOE3 contains 300 amino acid residues.
Formulation
Sterile filtered and lyophilized from a buffer of 20 mM sodium phosphate
Reconstitution
Centrifuge vial prior to opening. Add 5 mM Sodium Phosphate, pH 7.8 + 0.5 mM DTT to the vial to fully solubilize the protein to a concentration of 0.1-1.0 mg/ml. After complete solubilization of the protein, it can be further diluted into other aqueous buffers.
Storage and Stability
Store lyophilized protein at -20C. Reconstituted protein is stable for 1 week at 4C or in aliquots at -20C for longer storage. Avoid repeated freeze-thaw cycles.
GeneID
348
Source
E. coli
Molecular Weight
34.0 kDa
Purity
>90% as determined by SDS-PAGE and HPLC analyses
Endotoxin Level
<0.1 ng/ug of ApoE3
AA Sequence
MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH

Arbeitsanleitung

CS-CRA401B.pdf

Menge: 500 ug
Lieferbar: In stock
Listenpreis: 689,52 €
Preis: 689,52 €
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