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Recombinant Human BMP6 active

Recombinant Human BMP6 active

Hersteller	Cell Sciences
Kategorie	Proteins
Typ	Proteins
Specific against	Human
Menge	10 ug
Host	E.coli
ArtNr	CS-CRB138A
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Description	BMPs (bone morphogenetic proteins) belong to the TGF-a superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-6 contains a mixture of monomer (15 kDa), dimer (30 kDa), and multimers. The dimer is an active polypeptide chain containing 2X142 amino acid residues.
Formulation	Sterile filtered and lyophilized without additives
Reconstitution	Centrifuge vial prior to opening. Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future use.
Storage and Stability	The lyophilized protein is best-stored desiccated below 0C. Reconstituted BMP-4 should be stored in working aliquots at -20C. For long-term storage, it is recommended to add a carrier protein (0.1% BSA). Avoid repeated freeze-thaw cycles.
Source	E. coli
Molecular Weight	Mixture of monomer (15 kDa), dimer (30 kDa), and multimers.
Purity	>98% by SDS-PAGE and HPLC analyses
Endotoxin Level	< 0.1 ng/ug of protein
Biological Activity	The ED50 as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 ug/ml.