Vergleich

Recombinant Human CTLA4/CD152

ArtNr CS-CRC012B
Hersteller Cell Sciences
Menge 25 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% as determined by RP-HPLC and SDS-PAGE analyses
Sequence The sequence of the first five N-terminal amino acids is Lys-Ala-Met-His-Val.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products CD152, CTLA-4, CELIAC3, GSE, IDDM12, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated serine esterase-4, OTTHUMP00000163781, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Store lyophilized protein at -20C to -80C. Reconstituted protein is stable for 1 week in working aliquots. For long term storage, aliquot and store at -20C to -80C with a carrier protein (0.1% HSA or BSA) as a stabilizer. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight
80.0 kDa
Description
Recombinant human CTLA-4/CD152 is a homodimeric, glycosylated polypeptide chain. Each subunit (40 kDa) is fused to a polypeptide linker to the Fc portion of human IgG1. CTLA-4 is expressed in low copy number by T-cells only after activation, but it binds CD28-ligand with approximately 20-fold higher affinity than CD28. A soluble form of the extracellular domain of CTLA-4 has been shown to bind CD28-ligand with high avidity and to suppress T-cell-dependent antibody responses, in vivo . Large doses of this soluble protein also suppress responses to a second immunization.
Formulation
Lyophilized from a sterile filtered solution without additives
Reconstitution
Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Endotoxin Level
< 0.1 ng/ug of CTLA4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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