Recombinant Human CEBP alpha

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 50 ug
Host E.coli
ArtNr CS-CRC132B
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
CCAAT/enhancer binding protein(C/EBP) a is a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP a, b, g, d, that form homodimers and that form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein, a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBPs differ significantly in their physiological functions and in their downstream target genes. For example, mice lacking C/EBPa die shortly after birth due to severe hypoglycemia and the absence of glycogen storage in liver, whereas knockout of C/EBPb causes defects in female reproduction. CEBP-a Human Recombinant His-Tag fusion protein produced in, E. coli, is a single, non-glycosylated polypeptide chain containing amino acids 126 (aa 270-358) and having a MW = 14.5 kDa. The Recombinant Human CEBP-a was purified by proprietary chromatographic techniques.
Formulation
Sterile filtered liquid in 20 mM Tris-HCl, pH 7.5 + 0.1 M NaCl + 5 mM beta-mercaptoethanol
Storage and Stability
Store at 2-4C for up to 4 weeks or in working aliquots at -20C for longer storage. Add a carrier protein (0.1% HSA or BSA) as a stabilizer for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
GeneID
1050
Source
E. coli
Molecular Weight
14.5 kDa
Purity
> 95% as determined by SDS-PAGE analyses
Protein Accession No
NP_004355
AA Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGAG KAKKSVDKNS NEYRVRRERN NIAVRKSRDK AKQRNVETQQ KVLELTSDND RLRKRVEQLS RELDTLRGIF RQLPESSLVK AMGNCA
Menge: 50 ug
Lieferbar: In stock
Listenpreis: 428,68 €
Preis: 428,68 €
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