Recombinant Human Eotaxin 2

Eotaxin-2 (CCL24) is a novel CC chemokine recently identified. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the mouse homolog, without C-terminal truncation). CCL24 is a single non-glycosylated polypeptide chain containing 78 amino acids.

Lyophilized from a 0.2 um filtered concentrated (1.0 mg/mL) solution in 20 mM PB, pH 7.4 + 150 mM NaCl.

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

„1.0 ca. 104 IU/mg.