Recombinant Human FABP5

Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4C for a limited period of time, it does not show any change after two weeks at 4C. The lyophilized protein remains stable until the expiration date when stored at -20C. Avoid repeated freeze-thaw cycles.

Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). In an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity. Recombinant Human Epidermal Fatty Acid Binding Protein (FABP-5) is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids and having a total MW = 15200 Daltons.