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Recombinant Human IGFBP1

Recombinant Human IGFBP1

ArtNr	CS-CRI232B
Hersteller	Cell Sciences
Menge	25 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Endocrine Regulation of Lipid Metabolism
Typ	Proteins
Specific against	Human (Homo sapiens)
Purity	> 98% as determined by SDS-PAGE and HPLC analyses
Sequence	MGSSHHHHHH SSGLVPRGSH MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NG
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	IBP1, IGFBP-1, IGF-binding protein 1, IBP-1, AFBP, IGF-BP25, PP12, hIGFBP-1, alpha-pregnancy-associated endometrial globulin, amniotic fluid binding protein, binding protein-25, binding protein-26, binding protein-28, insulin-like growth factor-binding protein 1, OTTHUMP00000214348, OTTHUMP00000214349, placental protein 12, growth hormone independent-binding protein
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Storage Conditions	Store lyophilized protein below 0C. Reconstituted protein is stable for 1 week at 2-4C. For long term storage, aliquot and store at -20C. Avoid repeated freeze-thaw cycles.
Molecular Weight	27.57 kDa
Description	Human IGFBP1 is a 25.4 kDa cysteine rich polypeptide expressed in liver, decidual, and kidneys and is the most abundant IGFBP in amniotic fluid. Levels of IGFBP1 in serum are lowest after food. IGFBP1 binds both IGF1 and IGF2 with equal affinity. Phosphorylated IGFBP1 hinders IGF actions, whereas non-phosphorylated IGFBP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 255 amino acid residues with an N-terminal His-tag.
Formulation	Lyophilized from a sterile filtered solution with no additives
Reconstitution	Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration of 0.1-1.0 mg/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Biological Activity	Determined by its ability to inhibit IGF1 induced proliferation of NUC-1 cells. The ED50 is ca.100 ng/ml.
Endotoxin Level	< 0.1 ng/ug

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CS-CRI232B-datasheet.pdf

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Menge: 25 ug

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Lieferung vsl. bis 22.01.2026

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