Vergleich

Recombinant Human MCP4/CCL13

ArtNr CS-CRM005C
Hersteller Cell Sciences
Menge 1.0 mg
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity > 96% as determined by SDS-PAGE gel and HPLC analyses
Sequence QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products MCP-4, SCYL1, member 13, small inducible cytokine subfamily A (Cys-Cys), CKb10, MGC17134, NCC-1, NCC1, SCYA13, CK-beta-10, monocyte chemoattractant protein 4, monocyte chemotactic protein 4, new CC chemokine 1, small inducible cytokine A13
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Stable at 2-8C, but best kept desiccated -20C. Upon reconstitution, stable for up to 1 week at 2-8C. For longer term, store in working aliquots below -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
8.6 kDa
Description
MCP-4/CCL13 is a chemoattractant for monocytes and eosinophils, and activates basophils. In addition, it has been reported to be chemotactic for CD4+ and CD8+ T cells, with an activity almost equivalent to that of MCP-3. The bioactivities of CCL13 is most likely mediated by the CC chemokine receptors CCR-2 and CCR-3, both of which have been shown to bind CCL13.
Formulation
Lyophilized from a sterile filtered solution in 20 mM PB, pH 7.4, 130 mM NaCl.
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.
Biological Activity
Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 100 ng/ml
Endotoxin Level
Less than 1EU/ug of rHuMCP-4/CCL13 as determined by LAL method.

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Menge: 1.0 mg
Lieferbar: In stock
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