Recombinant Human Myostatin

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Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 10 ug
Host E.coli
ArtNr CS-CRMY00B
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Myostatin is a member of the TGF-beta superfamily that is essential for proper regulation of skeletal muscle mass in a number of species ranging from fish to humans. Myostatin is a secreted protein that negatively regulates skeletal muscle mass determining both muscle fiber number and size. Inhibition of myostatin can increase muscle mass in a number of animal models of human disease, including muscular dystrophy. Recombinant human Myostatin is a non-glycosylated homodimer, containing two 109 amino acid chains.
Formulation
Recombinant human Myostatin is lyophilized with no additives.
Reconstitution
Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with 20 mM HCl at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Storage and Stability
Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
GeneID
2660
Source
E. coli
Molecular Weight
24.8 kDa
Purity
95% determined by: Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Endotoxin Level
Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.
Biological Activity
The activity is determined by the inhibition of the proliferation of MPC-11 cells and is typically less than 20 ng/ml.
AA Sequence
DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS

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Menge: 10 ug
Lieferbar: In stock
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