Recombinant Human STK3/MST2 GST Active

Stable for 1 year in working aliquots at -80C. Avoid repeated freeze-thaw cycles.

Recombinant human full length STK3 with N-terminal GST tag. STK3 encodes a protein of 491 amino acids which contains an N-terminal catalytic domain characteristic of STKs. STK3 and STK4 share 94% amino acid identity in the catalytic domain and 78% identity overall. RAF1 has been shown to counteract apoptosis by suppressing the activation of mammalian sterile 20-like kinase. STK3 is a kinase that is activated by the proapoptotic agents, straurosporine, and FAS ligand. STK3 activation presumably allows cells to resist unfavorable environmental conditions.

249 nmol/min/mg