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Recombinant Human TGF-beta 3

Recombinant Human TGF-beta 3

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Hersteller	Cell Sciences
Kategorie	Proteins
Typ	Proteins
Specific against	Human
Menge	10 ug
Host	E.coli
ArtNr	CS-CRT004B
eClass 6.1	34160400
eClass 9.0	42020190
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Description	The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-beta isoforms (TGF-beta1, -beta2 and -beta3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-beta3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-beta3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant human TGF-beta3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains.
Formulation	Recombinant human TGF-beta3 is provided in a solution (0.25 mg/mL) that contains 20% Ethanol and 0.12% acetic acid (AcOH).
Reconstitution	Not applicable.
Storage and Stability	Stable at 2-4C for 1 year from date of purchase.
Concentration	0.25 mg/ml
GeneID	7043
Source	E. coli
Molecular Weight	25.5 kDa
Purity	Typically 98% determined by: Reducing and Non-reducing SDS-PAGE
Specific Activity	12.5 x 106 units/mg
Endotoxin Level	Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.
Biological Activity	The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
AA Sequence	ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS

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