Recombinant Human TGF-beta 3

The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.

The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-beta isoforms (TGF-beta1, -beta2 and -beta3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-beta3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-beta3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant human TGF-beta3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains.

Recombinant human TGF-beta3 is provided in a solution (0.25 mg/mL) that contains 20% Ethanol and 0.12% acetic acid (AcOH).

Not applicable.

12.5 x 106 units/mg