Recombinant Human VCAM1/CD106 His

VCAM1 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. VCAM-1 contains 6 or 7 immunoglobulin domains, and is expressed on both large and small vessels only after the endothelial cells are stimulated by cytokines. The protein has a number of functions including the regulation of leukocyte migration, leukocyte endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases (artherosclerosis and rheumatoid arthritis). VCAM1 Human Recombinant is expressed in, E. coli, containing 674 amino acids (a.a. 25-698) fused to an amino terminal hexahistidine tag, having a total MW of 78.8kDa.

Liquid in 10 mM Tris-HCl, pH 8 + 250 mM NaCl + 0.5 mM DTT + 1.5 mM cysteine + 50% glycerol