Recombinant Human Histidyl-tRNA Synthetase Sf9 His

Histidyl-tRNA Synthetase should be stored desiccated below -20C. Avoid repeated freeze-thaw cycles

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Histidyl-tRNA Synthetase is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Histidyl-tRNA Synthetase is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Recombinant Human Histidyl-tRNA Synthetase produced in baculovirus is a single, glycosylated, polypeptide chain having a MW = 58.3 kDa. It is fused to a 6x His Tag and purified by proprietary chromatographic techniques.