Native Mouse Fibrinogen *di

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Mouse
Menge 1.0 mg
Host Mouse
ArtNr CS-CRF135B
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Fibrinogen, also called Factor I, is the principal protein of vertebrate blood clotting forming a hexamer containing two sets of three different chains (alpha, beta, and gamma), linked to each other by disulfide bonds. The N-terminal sections of these three chains contain the Cysteines that participate in the cross-linking of the chains. The C-terminal parts of the alpha, beta and gamma chains contain a domain of about 225 amino acid residues, which can function as a molecular recognition unit, engage in protein-protein interactions, and bind carbohydrates. On the Fibrinogen alpha and beta chains, there is a small peptide sequence (called a Fibrinopeptide) that prevents Fibrinogen from spontaneously forming polymers with itself. Fibrinogen is the precursor of Fibrin. Fibrin, also called Factor Ia, is a fibrous protein involved in the clotting of blood, and is non-globular. Native Mouse Fibrinogen is prepared from fresh mouse plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography.
Formulation
Frozen liquid in 0.02 M Sodium Citrate-HCl, pH 7.4
Storage and Stability
Store product at -80C. Stable for 3 years from delivery. Thaw protein in a 37C water bath without agitation until completely liquid. Then, gently mix before use. Keep fibrinogen at 25-37C when in use. Aliquot and freeze the unused portion at -80C. Avoid repeated freeze-thaw cycles.
Concentration
>2.0 mg/ml
Source
Mouse plasma
Molecular Weight
340 kDa
Purity
>95% by SDS-PAGE
Specific Activity
100% Clottable
Endotoxin Level
<0.1 ng/ug of protein.

Arbeitsanleitung

CS-CRF135B.pdf

Menge: 1.0 mg
Lieferbar: In stock
Listenpreis: 501,47 €
Preis: 501,47 €
lieferbar

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Arne Pelz

sales@hoelzel.de