Recombinant West Nile Virus Pre-M His

Biomolecules

West Nile virus (WNV) is a virus of the family Flaviviridae part of the Japanese encephalitis (JE) antigenic complex of viruses. Image reconstructions and cryo-electron microscopy reveal a 45-50 nm virion covered with a relatively smooth protein surface. This structure is similar to virus, both belong to the genus flavivirus within the family Flaviviridae. WNV is a positive-sense, single strand of RNA, it is between 11, 000 and 12, 000 nucleotides long which encode seven non-structural proteins and three structural proteins. The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks, the capsid is contained within a host-derived membrane altered by two viral glycoproteins. The, E. coli, derived 20 kDa recombinant protein contains the West-Nile N-Terminal Pre-M Virus immunodominant regions. The protein is fused with 6x His tag.

Immunoreactive with sera of West Nile virus infected individuals.