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Recombinant Rat RANTES/CCL5

ArtNr CS-CRR002B
Hersteller Cell Sciences
Menge 20 ug
Kategorie
Typ Proteins
Specific against Rat (Rattus norvegicus)
Host E.coli
Purity 97% determined by HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Sequence SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products Rantes, small inducible cytokine A5, Scya5
Lieferbar
Manufacturer - Category
Biomolecules
Storage Conditions
Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Avoid repeated freeze-thaw cycles.
Molecular Weight
7.9 kDa
Description
Regulated Upon Activation Normal T cell Express Sequence (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after activation. RANTES is a promiscuous chemokine that signals through several G protein-coupled receptors, CCR5, CCR3, CCR1 and US28 (a viral receptor encoded by human CMV). The main function of RANTES is to recruit immune cells to the site of inflammation. Recombinant rat RANTES is a non-glycosylated protein, containing 68 amino acids.
Formulation
Recombinant rat RANTES is lyophilized with no additives.
Reconstitution
Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Biological Activity
The activity is determined by the ability to chemoattract primary human T cells and THP-1 cells at 1-10 ng/mL.
Endotoxin Level
Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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