8-Bromo-cAMP sodium salt

76939-46-3

C10H10BrN5NaO6P

H2O : >= 33.33 mg/mL (77.50 mM); DMSO : 125 mg/mL (290.64 mM; Need ultrasonic)

Stem Cell/Wnt; Protein Tyrosine Kinase/RTK

8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)^[1]. IC50 & Target: PKA^[1] In Vitro: 8-Bromo-cAMP sodium salt is a brominated derivative of cyclic AMP. 8-Bromo-cAMP sodium salt enhances the efficiency of cellular reprogramming. 8-Bromo-cAMP sodium salt improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. 8-Bromo-cAMP sodium salt inhibits proliferation, induce differentiation and apoptosis in a malignant glioma cell line (A-172) and an esophageal cancer cell line (Eca-109)^[1].