Minocycline (hydrochloride)

13614-98-7

C23H28ClN3O7

DMSO : 0.49 mg/mL (0.99 mM; Need ultrasonic and warming); H2O : 11.11 mg/mL (22.49 mM; Need ultrasonic)

Anti-infection

Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. IC50 Value: N/A Target: Antibacterial Minocycline acts as a matrix metalloproteinase (MMP) inhibitor; attenuates disease severity in mouse models of multiple sclerosis. Minocycline also inhibit the enzymatic activity of poly(ADP-ribose) polymerase-1 (PARP-1) and angiogenesis. In addition, Minocycline is suggested to down-regulate CD40L on T cells and inhibit the replication of SIV and HIV. Orally active and brain penetrant.