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Recombinant Human Platelet-Derived Growth Factor Alpha Polypeptide (a. a. 250)

Recombinant Human Platelet-Derived Growth Factor Alpha Polypeptide (a. a. 250)

ArtNr	DAG298
Hersteller	Creative Diagnostics
Menge	10 ug
Kategorie	Oncology By Cell Type Glioma Hematology Lymphoma Peptides & Proteins Peptides By Organ Skin Cancer Heart & Blood Cancer
Typ	Peptides
Format	Lyophilized
Specific against	other
Purity	>97%pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE). Endotoxin level isless than 0.1ng/ug (IEU/ug). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PDGFA,platelet-derived growth factor alpha polypeptide,Platelet-derived growthfactor subunit A,PDGF-1,Platelet-derived growth factor A chain,PDGFsubunit A,PDGF1,PDGF-A,PDGF A-chain,PDGF subunit A,OTTHUMP00000199955,OTTHUMP00000199956,platelet-derived growth factor alpha chain,platelet-derived growth factor alpha isoform 2 preproprotein,PlateletDerived Growth Factor AA,PDGF-AA,Platelet-derived growth factor,Plateletderived growth factor A chain precursor,Platelet derived growth factor alphapolypeptide,Platelet-derived growth factor alpha polypeptide
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Manufacturer - Applications	The ED50as determined by the dose-dependent proliferation of murine BALB/c 3T3indicator cells (measured by 3H-thymidine uptake) is <1ng/ml, corresponding to a specific activity of 1 MIU/mg. Each laboratory shoulddetermine an optimum working titer for use in its particular application.Other applications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20°C. After reconstitution, short term (up to 1 week) store at2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name	Platelet-Derived Growth Factor Alpha Polypeptide
Product Overview	Recombinant HumanPlatelet-Derived Growth Factor Alpha Polypeptide is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 125 amino acids and havinga total molecular weight of 28, 511 Da, was expressed in E. coli. The sequenceof the first five N-terminal amino acids was determined to beSer-Ile-Glu-Glu-Ala. Contains less than 1% dimers and aggregates.
Abbr	PDGFA (a.a. 250)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	PDGFAplatelet-derived growth factor alpha polypeptide [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_002607
Gene Information - Protein Refseq	NP_002598
Gene Information - MIM	173430
Gene Information - Pathway	Ceramide signalingpathway, Cytokine-cytokine receptor interaction, Cytokines and InflammatoryResponse, Down-stream signal transduction, Focal Adhesion, Formation ofPlatelet plug, Gap junction, Glioma, HTLV-I infection, Hemostasis, MAPKsignaling pathway, Melanoma, Pathways in cancer
Gene Information - Function	cell surfacebinding, collagen binding, eukaryotic cell surface binding, growth factoractivity, platelet-derived growth factor binding, platelet-derived growthfactor receptor binding, contributes_to platelet-derived growth factorreceptor binding, platelet-derived growth factor receptor binding, proteinheterodimerization activity, protein homodimerization activity
Antigen Description	Platelet-derived growth factor is apotent mitogen for cells of mesenchymal origin. Binding of this growth factorto its receptor elicits a variety of cellular responses. It is released byplatelets upon wounding and plays an important role in stimulating adjacentcells to grow and thereby heals the wound.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 10 ug

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Lieferung vsl. bis 27.11.2025

Express-Lieferung: 1 Tage sparen

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