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Recombinant Human Immunodeficiency Virus Type 2 Gp36, His-tagged

ArtNr DAG588
Hersteller Creative Diagnostics
Menge 1 mg
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen WB, ELISA
Specific against other
Konjugat/Tag HIS
Purity Purity determined by, SDS-PAGE and Western blot
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturer - Applications
Suitable, for use in ELISA and Western blot. Each laboratory should determine an, optimum working titer for use in its particular application. Other, applications have not been tested but use in such assays should not, necessarily be excluded.
Storage Conditions
Store, at –70C or below. Aliquot to avoid multiple freeze thaws.
Full name
Human Immunodeficiency Virus Glycoprotein 36
Product Overview
Recombinant, ecto-domain of HIV-2 gp36, contains a 6 histidine fusion partner and was, expressed in Pichia, pastoris, reacts with HIV-2 positive human sera and monoclonal antibodies as determined, by ELISA and Western blot.
Background - Introduction
Human, immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus, family) that causes acquired immunodeficiency syndrome (AIDS), a condition in, humans in which progressive failure of the immune system allows, life-threatening opportunistic infections and cancers to thrive. Infection, with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as, both free virus particles and virus within infected immune cells. The four, major routes of transmission are unsafe sex, contaminated needles, breast, milk, and transmission from an infected mother to her baby at birth, (perinatal transmission). Screening of blood products for HIV has largely, eliminated transmission through blood transfusions or infected blood products, in the developed world.
Background - Keywords
Gp36, HIV 2, Human, immunodeficiency virus 2, Human Immunodeficiency Virus Type 2, HIV-2 Gp36, Human Immunodeficiency Virus Type 2 Gp36, Retroviridae, Lentivirus
Abbr
HIV-2 Gp36, His-tagged
Manufacturer - Format
Purified, Liquid
Buffer
6M Urea, 0.02M, Tris-HCl, 0.5M Sodium chloride, pH 7.0 to 8.0 at room temperature
Concentration
Lot specific (Coomassie Plus)
Preservative
None
Antigen Description
HIV1 and HIV2 have similar gag (viral core) and pol, (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little, serologic cross-reactivity of the antibodies directed against the envelope, antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved, and elicits a type-specific antibody response. Hence, most licensed, diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific, antibodies. It is becoming important to differentiate between single, infection with either HIV1 or HIV2 and dual infection.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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Lieferung vsl. bis 18.12.2025 

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